Research Group

  • Overview
  • Datasets 12
  • People 14
  • Publications 4
  • Information Products 0
Using Embryonic Stem Cell Fate to Determine Potential Adverse Effects of Petroleum/Dispersant Exposure

Demetri D. Spyropoulos

Gulf of Mexico Research Initiative (GoMRI)

RFP-II

Dataset Available

Pygmy Sperm Whale induced Pluripotent Stem Cells Oil/Dispersant Toxicity Test

Authors: Temkin, A; Spyropoulos, D; Baatz J
Published On: Apr 10 2017 20:18 UTC
File Format: csv
DOI: 10.7266/N73B5XJ1
UDI: R2.x217.000:0001
File Size: 1.17 KB
Dataset Available

Alligator induced Pluripotent Stem Cell Oil/Dispersant Toxicity Test

Authors: Demetri D Spyropoulos, Lexi Temkin, Robert Bowers, John E Baatz
Published On: Apr 10 2017 19:39 UTC
File Format: csv
DOI: 10.7266/N73F4N06
UDI: R2.x217.000:0002
File Size: 1.16 KB
Dataset Available

Alligator Oil/Dispersant Exposure and Adipogenesis

Authors: Demetri Spyropoulos, Lexi Temkin, Robert Bowers, John Baatz
Published On: Feb 22 2016 16:46 UTC
File Format: Excel spreadsheet, pdf and docx
DOI: 10.7266/N7PG1PQH
UDI: R2.x217.000:0003
File Size: 295.13 MB
Dataset Available

Pygmy Sperm Whale Oil/Dispersant Exposure and Adipogenesis

Authors: Demetri Spyropoulos, Lexi Temkin, Robert Bowers, John Baatz
Published On: Feb 22 2016 19:08 UTC
File Format: Excel spreadsheet, pdf, tif, docx
DOI: 10.7266/N7JQ0Z1N
UDI: R2.x217.000:0004
File Size: 855.37 KB
Dataset Available

Human Adipocyte/Preadipocyte Gene Expression Assay

Authors: Demetri Spyropoulos, Lexi Temkin, Robert Bowers, John Baatz
Published On: Feb 22 2016 20:08 UTC
File Format: Excel spreadsheet, pdf and docx
DOI: 10.7266/N7F18WQ0
UDI: R2.x217.000:0005
File Size: 365.01 KB
Dataset Available

PPARγ and RXRα Ligand Binding Assays

Authors: Demetri Spyropoulos, Lexi Temkin, Robert Bowers, John Baatz
Published On: Feb 22 2016 22:35 UTC
File Format: Excel spreadsheet, pdf and docx
DOI: 10.7266/N798851H
UDI: R2.x217.000:0006
File Size: 46.82 KB
Dataset Available

PPARγ and RXRα Ligand Binding Assays: Corexit Components

Authors: Demetri Spyropoulos, Lexi Temkin, Robert Bowers, John Baatz
Published On: Feb 23 2016 16:54 UTC
File Format: Excel worksheet and docx
DOI: 10.7266/N75H7D8B
UDI: R2.x217.000:0007
File Size: 76.74 KB
Dataset Available

Effects of CWAF chemically enhanced water accommodated sub-fractions on peroxisome proliferator-activated receptor PPAR gamma binding.

Authors: John E. Baatz, Alexis Temkin, Demetri D. Spyropoulos
Published On: Feb 16 2016 21:54 UTC
File Format: csv, pdf, xlsx, docx
DOI: 10.7266/N71R6NH5
UDI: R2.x217.000:0008
File Size: 143.75 KB
Dataset Available

3t3L1 Cell DOSS Exposure and Adipogenesis

Authors: Lexi Temkin, Robert Bowers, Demetri Spyropoulos
Published On: Feb 17 2016 15:25 UTC
File Format: excel
DOI: 10.7266/N7X0651K
UDI: R2.x217.000:0009
File Size: 20.93 KB
Dataset Available

Estrogen Receptor 1 (ESR1; ERα), not ESR2 (ERβ), Modulates Estrogen-Induced Sex Reversal in the American Alligator, a Species With Temperature-Dependent Sex Determination

Authors: Kohnoo, Satomi and Guillette, LJ
Published On: Apr 11 2017 19:30 UTC
File Format: csv
DOI: 10.7266/N7ST7N7G
UDI: R2.x217.000:0010
File Size: 2.28 KB
Dataset Available

Dataset for: Toxic effects of chemical dispersant Corexit 9500 on water flea Daphnia magna

Authors: Kohno, Satomi
Published On: Jan 05 2017 20:15 UTC
File Format: xlsx
DOI: 10.7266/N7J964T5
UDI: R2.x217.000:0012
File Size: 72.12 KB
Dataset Available

DOSS Treated Mouse Plasma Adipokine and Cytokine Levels

Authors: Spyropoulos, D; Temkin, A; Baatz, J
Published On: May 15 2017 22:06 UTC
File Format: csv
DOI: 10.7266/N7FT8JF6
UDI: R2.x217.000:0013
File Size: 1.87 KB

John E. Baatz
Professor
Medical University of South Carolina / Marine Biomedicine and Environmental Sciences

baatzje@musc.edu

Melissa Bernhard

College of Charleston / Graduate Program in Marine Biology

bernhardm@g.cofc.edu

Robert R. Bowers

Medical University of South Carolina / Department of Pathology and Laboratory Medicine

bowersrr@musc.edu

Theresa M. Cantu

Medical University of South Carolina / Marine Biomedicine and Environmental Sciences

cantuT@musc.edu

Jessica A. Cloy-McCoy

Medical University of South Carolina / Marine Biomedicine and Environmental Sciences

cloy@musc.edu

Debra L. Ellisor

Medical University of South Carolina / Department of Pathology and Laboratory Medicine

ellisord@musc.edu

Beth Hansell

Medical University of South Carolina / Department of Pathology and Laboratory Medicine

hansellb@musc.edu

Kevin Hildreth

Medical University of South Carolina / Department of Pathology and Laboratory Medicine

hildretk@musc.edu

Satomi Kohno
Assistant Professor
Medical University of South Carolina / Hollings Marine Lab

kohno@musc.edu

Nicole McNabb

College of Charleston / Graduate Program in Marine Biology

mcnabbna@g.cofc.edu

Itzel Sifuentes Romero

Medical University of South Carolina / Department of Pathology and Laboratory Medicine

romeroi@musc.edu

Demetri D. Spyropoulos
Associate Professor
Medical University of South Carolina / Marine Biomedicine and Environmental Sciences

spyropdd@musc.edu

Alexis M. Temkin

Medical University of South Carolina / Marine Biomedicine and Environmental Sciences

temkin@musc.edu

Cameron Williams

College of Charleston / Graduate Program in Marine Biology

williamsce1@g.cofc.edu

Bowers, R. R., Temkin, A. M., Guillette, L. J., Baatz, J. E., & Spyropoulos, D. D. (2016). The commonly used nonionic surfactant Span 80 has RXRα transactivation activity, which likely increases the obesogenic potential of oil dispersants and food emulsifiers. General and Comparative Endocrinology, 238, 61–68. doi:10.1016/j.ygcen.2016.04.029

Kohno, S., Bernhard, M. C., Katsu, Y., Zhu, J., Bryan, T. A., Doheny, B. M., … Guillette, L. J. (2015). Estrogen Receptor 1 (ESR1; ERα), not ESR2 (ERβ), Modulates Estrogen-Induced Sex Reversal in the American Alligator, a Species With Temperature-Dependent Sex Determination. Endocrinology, 156(5), 1887–1899. doi:10.1210/en.2014-1852

Temkin, A. M., Bowers, R. R., Magaletta, M. E., Holshouser, S., Maggi, A., Ciana, P., … Spyropoulos, D. D. (2015). Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen. Environmental Health Perspectives, 124(1). doi:10.1289/ehp.1409672

Toyota, K., McNabb, N. A., Spyropoulos, D. D., Iguchi, T., & Kohno, S. (2016). Toxic effects of chemical dispersant Corexit 9500 on water flea Daphnia magna . Journal of Applied Toxicology, 37(2), 201–206. doi:10.1002/jat.3343